HSV vector services
Large payloads without compromise.
When your construct exceeds AAV or LV limits, HSV lets you test the full design instead of splitting or trimming.
One construct. Fewer workarounds. Clearer readouts.
When payload limits force compromises
Splitting constructs turns delivery into the confounder.
Design constraints
- Construct won't fit even after trimming
- Forced to drop controls or regulatory elements
- Each iteration requires re-architecting delivery
Impact on results
- Co-transduction lowers effective take rate
- Multiple doses add cost and variability
- Failure becomes ambiguous: biology or delivery?
HSV: deliver the complete design
Up to ~150 kb payload capacity means you can test what you actually want to build.
Full construct
Stop trimming biology to fit vector limits.
Simpler dosing
One vector instead of multi-vector strategies.
Interpretable data
Know if the biology works without delivery confounds.
Vector comparison
| Feature | HSV | LV | AAV |
|---|---|---|---|
| Payload | ~150 kb | ~8-9 kb | ~4.7 kb |
| Integration | Episomal | Integrating | Non-integrating |
| Primary use | Large constructs, neurons | Ex vivo engineering | In vivo delivery |
| Considerations | Helper systems required | Insertional risk mitigation | Limited cargo, may need splitting |
Get in touch
Email us at info@braidingbio.com or fill out the form below.
We'll respond within 24 hours.
What to include
- Construct length and key features
- Promoter and regulatory elements
- Target cell type and MOI range
- QC needs (titer, purity, sterility)
- Desired timeline